Many times breakthrough technology emerges from an innocuous source. One such example is tissue nutrient solution (TNS), which originated from commercial collagen production. When creating collagen in vitro, human fibroblasts are placed in a nutrient rich medium. A shock to this system is executed with the intention of triggering fibroblast production of growth factors that naturally stimulate collagen production – which is where TNS was first discovered. SkinMedica, Inc. (Carlsbad, Calif.), has harnessed this physiologically balanced solution into a new skincare product providing natural restoration and revitalization.